Recruitment

10 international PhD positions to develop prokaryote proteomics at high temperature for single cells

Application Deadline: March 15, 2024 - SUBMISSIONS SYSTEM NOW CLOSED

These positions are provided by PROHITS, a European MSCA Doctoral Network project. The interdisciplinary research aim of PROHITS is the integration of experimental and computational approaches that can resolve the proteome of prokaryotes at single cell level, and at a range of temperatures, in order to improve our understanding of thermophile biology and to guide the optimized design of cell factories. The project will involve the development of microfluidics, mass spectrometry (MS) and associated bioinformatics to handle single prokaryotic cells, as well as MS-based thermal proteome profiling (TPP) to study the thermal response of the proteome of thermophiles. These data will be used to understand the in vivo thermal stability of proteins, and create genome-scale models of thermophiles to optimize them as cell factories.

PROHITS is a collaborative project between eleven participant organisations from six countries, including both academia and biotech industry, that will offer a comprehensive and cross-disciplinary structured curriculum for doctoral students. 10 fellowships (for DCs, Doctoral Candidates) are available in the areas of microfluidics, mass spectrometry, synthetic biology, bioinformatics and genome modelling:

Candidates must be in possession of a Master’s Degree (or equivalent) in chemistry, biochemistry, physical, life or biomedical sciences, or computational or mathematical sciences as requested in the skills and experience of the respective DC description, enabling them to enroll in a Doctoral Programme by the recruitment date. The candidate must not have resided or carried her/his main activity (studies, work, etc.) at the country of recruitment for more than 12 months in the 36 months immediately prior to the recruitment date. The candidate must not hold a Doctoral degree by the time of recruitment date (i.e. by the start of the contract).

Applications must be submitted online in English following the instructions and respecting the conditions at https://bit.ly/prohits. The deadline for applications was 15/03/2024 at 23:59 (CET)

Further general information about the PROHITS project: http://prohits.eu

ADDENDUM

The DC positions will be fully funded for a period of 3 years via the standard Marie Curie allowances (if needed, the 4th year will be covered locally according to the common national rates). All DCs will receive a mobility allowance (600€, monthly gross) and a country-adjusted living allowance*. DCs that are married (or have an equivalent status as recognized by their country of origin) and/or have kids will be eligible to receive a family allowance of 660€, monthly gross.

*The country-adjusted living allowance before all the compulsory deductions under national legislation can be found below. Note that the provided figures are estimated and can vary based on local deduction schemes. Selected candidates will be provided with the detailed information during the selection process.

  • Belgium: 3400€, monthly gross
  • Norway: 4375.8€, monthly gross
  • Austria: 3614.2€, monthly gross
  • France: 3957.6€, monthly gross
  • Hungary: 2448€, monthly gross

Open positions

No open positions currently.

Closed positions

[DC1] Prediction and interpretation of thermophilic proteins

Application Deadline: March 15, 2024

(3 months, 1 week ago)

Type: Computational
Affiliation(s): Vrije Universiteit Brussel
Starting date: Sept. 1, 2024
Location: Bio2Byte group; (IB)2; VUB, Brussels, Belgium

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[DC2] Thermal stress response of thermophiles

Application Deadline: March 15, 2024

(3 months, 1 week ago)

Type: Experimental
Affiliation(s): Vrije Universiteit Brussel
Starting date: Sept. 1, 2024
Location: Research Group of Microbiology; VUB, Brussels, Belgium

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[DC3] Single prokaryote cell MS data analysis

Application Deadline: March 15, 2024

(3 months, 1 week ago)

Type: Computational
Affiliation(s): Vlaams Instituut voor Biotechnologie Universiteit Gent
Starting date: Sept. 1, 2024
Location: CompOmics group; VIB-UGent Center for Medical Biotechnology, VIB and Ghent University, Ghent, Belgium

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[DC4] Mass spectrometry thermal proteome profiling data analysis and visualisation

Application Deadline: March 15, 2024

(3 months, 1 week ago)

Type: Computational
Affiliation(s): Universitetet i Bergen
Starting date: Sept. 1, 2024
Location: Proteomics Unit, Department of Biomedicine, University of Bergen, Norway

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[DC5] Genome-scale network models

Application Deadline: March 15, 2024

(3 months, 1 week ago)

Type: Computational
Affiliation(s): Universität Wien
Starting date: Sept. 1, 2024
Location: University of Vienna; Vienna, Austria

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[DC6] Thermal proteome profiling of thermophilic bacteria

Application Deadline: March 15, 2024

(3 months, 1 week ago)

Type: Experimental
Affiliation(s): Centre National De La Recherche Scientifique Université de Strasbourg
Starting date: Sept. 1, 2024
Location: LSMBO; IPHC; CNRS, Université de Strasbourg, Strasbourg, France

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[DC7] MS methods development for thermal proteome profiling and single cell analysis

Application Deadline: March 15, 2024

(3 months, 1 week ago)

Type: Experimental
Affiliation(s): Centre National De La Recherche Scientifique Université de Strasbourg
Starting date: Sept. 1, 2024
Location: LSMBO; IPHC; CNRS, Université de Strasbourg, Strasbourg, France.

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[DC8] Optimisation of cell factories

Application Deadline: March 15, 2024

(3 months, 1 week ago)

Type: Experimental
Affiliation(s): NovoArc GmbH
Starting date: Sept. 1, 2024
Location: NovoArc GmbH; Vienna, Austria

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[DC9] Microfluidics cell separation workflow development and integration with MS instrumentation

Application Deadline: March 15, 2024

(3 months, 1 week ago)

Type: Experimental
Affiliation(s): Cellenion SASU Université de Strasbourg
Starting date: Sept. 1, 2024
Location: Cellenion, Lyon, France; LSMBO; IPHC; CNRS, Université de Strasbourg, Strasbourg, France.

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[DC10] Optimisation of sample preparation and examination of the thermal response of selected thermophilic organisms

Application Deadline: March 15, 2024

(3 months, 1 week ago)

Type: Experimental
Affiliation(s): Debreceni Egyetem
Starting date: Sept. 1, 2024
Location: University of Debrecen; Debrecen, Hungary

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